A cytogenetic study of Down syndrome determined that 46 of 1021 cases were the result of translocations. The most frequent translocation was symbolized as t(14;21). A. What does t(14;21) mean? B. How many chromosomes total would you expect to be present in a Down syndrome individual with this translocation (normal humans have 46)? C. Draw the complement of chromosomes 14 and 21 in a Down syndrome translocation individual. (Hint: they’re diploid for 14.) D. Draw the chromosomes 14 and 21 in the normal carrier of the t(14;21) translocation. E. How many chromosomes total would you expect to be present in a t(14;21) carrier?