Explain what classifies a mutation as “temperature‑sensitive” by comparing phenotype(s) with a wildtype allele. How is this type of phenotype explained by protein behaviour? Would the following types of mutations most likely have: severe effects, mild effects, or no effect on protein function? Briefly explain your answers. Note that there may be more than one correct answer, but you need only to give one sensible answer and explain your reasoning. [6 marks] A nonsense mutation occurring in sequences encoding amino acids near the carboxy terminus of the protein A missense mutation affecting the active site of the protein A frameshift mutation near the 5’ end of the open reading frame